James  M.  Hill , Ph.D.

As of January 14, 2010, Dr. Hill has 4,732 cumulative citations based on Science Citation Index. These include 32 publications with greater than 50 citations; 14 with 100 citations or more; 7 with 150 citations; and 4 with greater than 250 citations.

Clement C, Bhattacharjee PS, Kaufman HE, Hill JM. Heat-induced reactivation of HSV-1 in latently infected mice: Upregulation in the trigeminal ganglia of predominantly CD83 and other immune response genes and their potential role in the viral LAT-ICPO locus. Invest Ophthalmol Vis Sci 50:2855-61, 2009.

Bhattacharjee PS, Neumann DM, Foster TP, Clement C, Singh G, Thompson HW, Kaufman HE, Hill JM. Effective treatment of ocular HSK with a human apolipoprotein E mimetic peptide in a mouse eye model. Invest Ophthalmol Vis Sci, 49(10)4263-8, 2008. PMID: 18515564

Hill JM, Ball MJ, Neumann DM, Azcuy AM, Bhattacharjee PS, Bouhanik S, Clement C, Lukiw WJ, Foster TP, Kumar M, Kaufman HE, Thompson TW. The high prevalence of HSV-1 DNA in human trigeminal ganglia is not a function of age or gender. J Virol, 82(16):8230-34, 2008. http://jvi.asm.org/cgi/reprint/JVI.00686-08v1?view=long&pmid=18550674

Bhattacharjee PS, Neumann DM, Foster TP, Bouhanik S, Clement C, Vinay D, Thompson HW, Hill JM: Effect of human apolipoprotein E genotype on the pathogenesis of experimental ocular HSV-1. Exp Eye Res, 87:122-30, 2008.  http://www.ncbi.nlm.nih.gov/pubmed/18572164?dopt=Citation

Giordani NV, Neumann DM, Bhattacharjee PS, McAnany PK, Hill JM, Bloom DC. During HSV-1 latency in rabbits, an inability to express LAT corresponds to an increased repression of lytic genes: J Virol, 82(12):6056-60, 2008. http://jvi.asm.org/cgi/content/full/82/12/6056?view=long&pmid=18400860

Clement C, Popp MP, Bloom D, Schultz G, Liu L, Neumann DM, Bhattacharjee PS, Hill JM. Microarray analysis of host gene expression for comparison between naïve and HSV-1 latent rabbit TG. Mol Vis, 14:1208-1220, 2008. http://www.molvis.org/molvis/v14/a142 

Toma HS, Murina AT, Areaux RG, Neumann DM, Bhattacharjee PS, Foster TP, Kaufman HE, Hill JM:  Ocular HSV-1 latency, reactivation and recurrent disease. Sem Ophthalmol, 23(4):249-73, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18584563?dopt=Citation

Neumann DM, Bhattacharjee PS, Giordani NV, Bloom DC, Hill JM. In vivo changes in the patterns of chromatin structure associated with the latent herpes simplex virus type 1 genome in mouse trigeminal ganglia can be detected at early times after butyrate treatment. J Virol 81:13248-13253, 2007. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17881451

Neumann, DM, Bhattacharjee PS, Hill, JM. Sodium butyrate: A chemical inducer of in vivo reactivation of HSV-1 in the ocular mouse model. J Virol 81:6106-6110, 2007.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17360760

Cui JG, Hill JM, Zhao Y, Lukiw WJ: Expression of inflammatory genes in the primary visual cortex of late-stage Alzheimer’s disease. NeuroReport. 18: 115-119, 2007.  

Friedman DA, Lukiw WJ, Hill JM: Apolipoprotein E ε4 offers protection against age-related macular degeneration, Med Hypotheses 68: 1047-1055, 2007.  PM:17141963

Hill JM , Bhattacharjee PS, Neumann DM: Apolipoprotein E alleles can contribute to the pathogenesis of numerous clinical conditions including HSV-1 corneal disease. Exp Eye Res 84:801-811, 2007. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17007837

Booth BA, Denham LV, Bouhanik S, Jacob JT, Hill JM.  Sustained release ophthalmic drug delivery systems for treatment of macular disorders:  Present and future applications.  Drug Aging 24:581-602, 2007.  PM:17658909 

Pinnoji RC, Bedadala GR, George B, Holland TC, Hill JM, Hsia SV: Repressor element-1 silencing transcription factor/neuronal restrictive silencer factor (REST/NRSF) can regulate HSV-1 immediate-early transcription via histone modification. Virol J 4:56, 2007.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17555596

Myles ME, Neumann DM, Hill JM: Recent progress in ocular drug delivery for posterior segment disease: emphasis on iontophoresis. Adv Drug Deliver Rev 57:2063-2079, 2006. PM:15254144

Kammerman, EM, Neumann DM, Ball MJ, Lukiw W, Hill, JM: Senile plaques in Alzheimer’s diseased brain: possible association of beta-amyloid with HSV-1 L-particles. Med Hypotheses, 66: 294-299,2006. PM:16242250

Bhattacharjee PS,Neumann DM,Stark D, Thompson HW, Hill JM: Apolipoprotein E modulates establishment of HSV-1 latency and survival in a mouse ocular model. Curr Eye Res, 31:703-708, 2006. PM:16966142 

Hill JM , Gebhardt BM, Azcuy AM, Matthews KE, Lukiw WJ, Steiner I, Thompson HW, Ball MJ: Can a herpes simplex virus type 1 neuroinvasive score be correlated to other risk factors in Alzheimer’s disease? Med Hypotheses 64:320-327, 2005.  PM:15607565 

Danaher RJ, Jacob RJ, Steiner MR, Allen WR, Hill JM, Miller CS: Histone deacetylation inhibitors induce reactivation of herpes simplex virus type 1 in a latency-associated transcript (LAT)-independent manner in neuronal cells. J Neurovirology 11:306-317, 2005. PM:16036811